Linked Life Data

20466524

Source:http://linkedlifedata.com/resource/pubmed/id/20466524

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2010-5-24
pubmed:abstractText
A controllable fabrication of superhydrophobic surface on titanium biomedical implants was successfully developed to improve the blood compatibility and anti-coagulation performance of biomedical implants. The electrochemical anodization was employed to form a layer of TiO(2) nanotubes on the titanium substrate, and then a hydrophobic monolayer was self-assembled on the nanotube surface. The morphology and wettability of the nanotube arrays were investigated by scanning electron microcopy and water drop contact angle measurement, respectively. From the in vitro blood compatibility evaluation, it was observed that not only very few of platelets were attached onto the superhydrophobic surface, but also the attached platelets were not activated in this condition. Comparatively, a large number of platelets adhered and spread out on both the bare titanium substrate and the superhydrophilic surface which was obtained by exposing the TiO(2) nanotubes under a UV irradiation. The results indicated that the superhydrophobic TiO(2) nanotube layers exhibited excellent blood compatibility and remarkable performance in preventing platelets from adhering to the implant surface. Therefore, the construction of superhydrophobic surface on biomedical implants could pave a way to improve the blood compatibility of the biomedical devices and implants.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1873-4367
pubmed:author
pubmed:copyrightInfo
Copyright 2010. Published by Elsevier B.V.
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
79
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
309-13
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
A novel electrochemical strategy for improving blood compatibility of titanium-based biomaterials.
pubmed:affiliation
State Key Laboratory of Physical Chemistry of Solid Surfaces, and Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't