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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-8-30
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pubmed:abstractText |
Adverse drug reactions may be manifested through changes in microvascular function (e.g. angioedema) or by subtle modification of the mechanisms controlling vascular tone, such as flow-mediated dilatation. Until now the early detection of such adverse drug reactions has been hampered by the lack of a predictive in vitro model. This in vitro model can be utilised to test potential effect of drugs on the normal responses of the vascular system.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1873-488X
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2010 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
40-6
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pubmed:meshHeading |
pubmed-meshheading:20435153-15-Hydroxy-11 alpha,9...,
pubmed-meshheading:20435153-Acetylcholine,
pubmed-meshheading:20435153-Arteries,
pubmed-meshheading:20435153-Capillary Permeability,
pubmed-meshheading:20435153-Enzyme Inhibitors,
pubmed-meshheading:20435153-Hemostatics,
pubmed-meshheading:20435153-Humans,
pubmed-meshheading:20435153-Ivermectin,
pubmed-meshheading:20435153-Microvessels,
pubmed-meshheading:20435153-Muscle, Smooth, Vascular,
pubmed-meshheading:20435153-Myography,
pubmed-meshheading:20435153-NG-Nitroarginine Methyl Ester,
pubmed-meshheading:20435153-Pressure,
pubmed-meshheading:20435153-Thrombin,
pubmed-meshheading:20435153-Vasoconstrictor Agents,
pubmed-meshheading:20435153-Vasodilation,
pubmed-meshheading:20435153-Vasodilator Agents
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pubmed:articleTitle |
A novel system for the investigation of microvascular dysfunction including vascular permeability and flow-mediated dilatation in pressurised human arteries.
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pubmed:affiliation |
Biopta Ltd, Weipers Centre, Garscube Estate, Bearsden Road, Glasgow, G61 1QH, UK.
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pubmed:publicationType |
Journal Article
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