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| pubmed-article:20434371 | lifeskim:mentions | umls-concept:C0145946 | lld:lifeskim |
| pubmed-article:20434371 | lifeskim:mentions | umls-concept:C0007193 | lld:lifeskim |
| pubmed-article:20434371 | lifeskim:mentions | umls-concept:C0032405 | lld:lifeskim |
| pubmed-article:20434371 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:20434371 | lifeskim:mentions | umls-concept:C1428200 | lld:lifeskim |
| pubmed-article:20434371 | lifeskim:mentions | umls-concept:C1622891 | lld:lifeskim |
| pubmed-article:20434371 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:20434371 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:20434371 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:20434371 | pubmed:dateCreated | 2011-2-7 | lld:pubmed |
| pubmed-article:20434371 | pubmed:abstractText | Previously, we demonstrated that inhibition of poly(ADP-ribose) polymerase (PARP) exerts protective effects against high-fat (HF) diet-induced atherogenesis in part by increasing tissue inhibitor of metalloproteinase (TIMP)-2 expression. Given that characteristics of dilated cardiomyopathy closely associate with atherosclerosis and are mediated by an imbalance between matrix metalloproteinases (MMPs) and TIMPs, we hypothesized that PARP-1 gene deletion may protect against HF-induced cardiac hypertrophy and dilatations by altering TIMP-2/MMPs balance in favor of a maintenance of tissue homeostasis. | lld:pubmed |
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| pubmed-article:20434371 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:20434371 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:20434371 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:20434371 | pubmed:issn | 1879-1336 | lld:pubmed |
| pubmed-article:20434371 | pubmed:author | pubmed-author:BoularesA... | lld:pubmed |
| pubmed-article:20434371 | pubmed:author | pubmed-author:MatrouguiKhal... | lld:pubmed |
| pubmed-article:20434371 | pubmed:author | pubmed-author:ZerfaouiMoura... | lld:pubmed |
| pubmed-article:20434371 | pubmed:author | pubmed-author:LazartiguesEr... | lld:pubmed |
| pubmed-article:20434371 | pubmed:author | pubmed-author:KayeAlan DAD | lld:pubmed |
| pubmed-article:20434371 | pubmed:author | pubmed-author:HansChetan... | lld:pubmed |
| pubmed-article:20434371 | pubmed:author | pubmed-author:FengYumeiY | lld:pubmed |
| pubmed-article:20434371 | pubmed:author | pubmed-author:TroxclairDana... | lld:pubmed |
| pubmed-article:20434371 | pubmed:author | pubmed-author:KimHogyoungH | lld:pubmed |
| pubmed-article:20434371 | pubmed:author | pubmed-author:JuJihangJ | lld:pubmed |
| pubmed-article:20434371 | pubmed:author | pubmed-author:NauraAmarjit... | lld:pubmed |
| pubmed-article:20434371 | pubmed:author | pubmed-author:SiddiquiDanis... | lld:pubmed |
| pubmed-article:20434371 | pubmed:copyrightInfo | Copyright © 2011 Elsevier Inc. All rights reserved. | lld:pubmed |
| pubmed-article:20434371 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:20434371 | pubmed:volume | 20 | lld:pubmed |
| pubmed-article:20434371 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:20434371 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:20434371 | pubmed:pagination | e57-68 | lld:pubmed |
| pubmed-article:20434371 | pubmed:dateRevised | 2011-9-26 | lld:pubmed |
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| pubmed-article:20434371 | pubmed:articleTitle | Opposing roles of PARP-1 in MMP-9 and TIMP-2 expression and mast cell degranulation in dyslipidemic dilated cardiomyopathy. | lld:pubmed |
| pubmed-article:20434371 | pubmed:affiliation | Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, LA, USA. chetan.hans@nationwidechildrens.org | lld:pubmed |
| pubmed-article:20434371 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:20434371 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:20434371 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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