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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-7-8
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pubmed:abstractText |
Maternal hyperglycemia increases the risk of congenital malformations. Epigallocatechin-3-gallate (EGCG), a natural antioxidant purified from green tea, inhibits oxidative stress signaling. We propose that EGCG prevents hyperglycemia-induced malformation via inhibition of oxidative stress signaling. The objective of this study is to examine the effect of EGCG on hyperglycemia-induced adverse effects during embryonic development.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-10102273,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-10331421,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-12058035,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-12375679,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-15746699,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-16364532,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-16387402,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-16410036,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-16458664,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-16574700,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-17021948,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-17449011,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-18166327,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-18177823,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-18223030,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-18674752,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-19194987,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-8623857,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-8982267,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-9038867,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-9485543,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-9614603,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-9669757,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20417490-9818799
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1097-6868
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pubmed:author |
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pubmed:copyrightInfo |
Copyright (c) 2010 Mosby, Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
203
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
75.e1-6
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pubmed:dateRevised |
2011-8-1
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pubmed:meshHeading |
pubmed-meshheading:20417490-Animals,
pubmed-meshheading:20417490-Antioxidants,
pubmed-meshheading:20417490-Blotting, Western,
pubmed-meshheading:20417490-Catechin,
pubmed-meshheading:20417490-Disease Models, Animal,
pubmed-meshheading:20417490-Embryonic Development,
pubmed-meshheading:20417490-Female,
pubmed-meshheading:20417490-Fetus,
pubmed-meshheading:20417490-Forkhead Transcription Factors,
pubmed-meshheading:20417490-Hyperglycemia,
pubmed-meshheading:20417490-Oxidative Stress,
pubmed-meshheading:20417490-Phosphorylation,
pubmed-meshheading:20417490-Pregnancy,
pubmed-meshheading:20417490-Proto-Oncogene Proteins c-akt,
pubmed-meshheading:20417490-Rats,
pubmed-meshheading:20417490-Rats, Sprague-Dawley,
pubmed-meshheading:20417490-Signal Transduction,
pubmed-meshheading:20417490-Yolk Sac
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pubmed:year |
2010
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pubmed:articleTitle |
Epigallocatechin-3-gallate ameliorates hyperglycemia-induced embryonic vasculopathy and malformation by inhibition of Foxo3a activation.
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pubmed:affiliation |
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, N.I.H., Extramural
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