Linked Life Data

20406540

Source:http://linkedlifedata.com/resource/pubmed/id/20406540

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2010-4-21
pubmed:abstractText
The Rapid Stat assay, a point-of-collection drug-testing device for detection of amphetamines, cannabinoids, cocaine, opiates, methadone, and benzodiazepines in oral fluid, was evaluated for cannabis and amphetamine-type stimulants. The Rapid Stat tests (n = 134) were applied by police officers in routine traffic checks. Oral fluid and blood samples were analyzed using gas chromatography-mass spectrometry (GC-MS) for Delta(9)-tetrahydrocannabinol, amphetamine, methamphetamine, methylenedioxymethamphetamine, methylenedioxyethylamphetamine, and methylenedioxyamphetamine. The comparison of GC-MS analysis of oral fluid with the Rapid Stat results for cannabis showed a sensitivity of 85%, a specificity of 87%, and a total confirmation rate of 87%. When compared with serum, the sensitivity of the cannabis assay decreased to 71%, the specificity to 60%, and the total confirmation rate to 66%. These findings were possibly caused by an incorrect reading of the THC test results. Comparison of the Rapid Stat amphetamine assay with GC-MS in oral fluid showed a sensitivity of 94%, a specificity of 97%, and a total confirmation rate of 97%. Compared with serum, a sensitivity of 100%, a specificity of 90%, and a total confirmation rate of 92% was found. The amphetamine assay must, therefore, be regarded as satisfactory.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1945-2403
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
155-61
pubmed:dateRevised
2011-5-10
pubmed:meshHeading
pubmed-meshheading:20406540-Amphetamine, pubmed-meshheading:20406540-Amphetamine-Related Disorders, pubmed-meshheading:20406540-Amphetamines, pubmed-meshheading:20406540-False Negative Reactions, pubmed-meshheading:20406540-False Positive Reactions, pubmed-meshheading:20406540-Gas Chromatography-Mass Spectrometry, pubmed-meshheading:20406540-Humans, pubmed-meshheading:20406540-Immunoassay, pubmed-meshheading:20406540-Marijuana Abuse, pubmed-meshheading:20406540-Methamphetamine, pubmed-meshheading:20406540-N-Methyl-3,4-methylenedioxyamphetamine, pubmed-meshheading:20406540-Predictive Value of Tests, pubmed-meshheading:20406540-Saliva, pubmed-meshheading:20406540-Sensitivity and Specificity, pubmed-meshheading:20406540-Solid Phase Extraction, pubmed-meshheading:20406540-Substance Abuse Detection, pubmed-meshheading:20406540-Tetrahydrocannabinol
pubmed:year
2010
pubmed:articleTitle
Detection of Delta9-tetrahydrocannabinol and amphetamine-type stimulants in oral fluid using the Rapid Stat point-of-collection drug-testing device.
pubmed:affiliation
Institute of Legal Medicine, Johannes Gutenberg-University Mainz, Am Pulverturm 3, Mainz, Germany. roehrich@uni-mainz.de
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Evaluation Studies