Source:http://linkedlifedata.com/resource/pubmed/id/20384523
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2010-4-13
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pubmed:abstractText |
In advanced renal cell cancer and malignant melanoma, the current FDA approved immune modulators, such as IL-2, are the only agents which provide a durable complete remission. These responses, however, occur in < 10% of treated patients and their applicability is limited to selected patients because of their toxicity. The identification of new immunotherapeutic agents with an improved response rate and toxicity profile would represent a significant advancement in the treatment of these malignancies.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1744-7682
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
807-17
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pubmed:dateRevised |
2011-8-25
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pubmed:meshHeading |
pubmed-meshheading:20384523-Animals,
pubmed-meshheading:20384523-Antineoplastic Agents,
pubmed-meshheading:20384523-Carcinoma, Renal Cell,
pubmed-meshheading:20384523-Clinical Trials, Phase I as Topic,
pubmed-meshheading:20384523-Clinical Trials, Phase II as Topic,
pubmed-meshheading:20384523-Evidence-Based Medicine,
pubmed-meshheading:20384523-Humans,
pubmed-meshheading:20384523-Immunotherapy,
pubmed-meshheading:20384523-Interleukins,
pubmed-meshheading:20384523-Kidney Neoplasms,
pubmed-meshheading:20384523-Lymphoma, Non-Hodgkin,
pubmed-meshheading:20384523-Melanoma,
pubmed-meshheading:20384523-Mice,
pubmed-meshheading:20384523-Recombinant Proteins,
pubmed-meshheading:20384523-Treatment Outcome
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pubmed:year |
2010
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pubmed:articleTitle |
Interleukin-21: updated review of Phase I and II clinical trials in metastatic renal cell carcinoma, metastatic melanoma and relapsed/refractory indolent non-Hodgkin's lymphoma.
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pubmed:affiliation |
Division of Hematology and Oncology, Department of Internal Medicine, University of Kansas Medical Center, 2330 Shawnee Mission Parkway, Mail Stop 5003, Westwood, KS 66202, USA. pvanveldhuizen@kumc.edu
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pubmed:publicationType |
Journal Article,
Review
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