Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2010-4-19
pubmed:abstractText
The past two decades have witnessed an increasing appreciation of the role of the tumor microenvironment, of genetic and epigenetic alterations in normal cells adjacent to tumors and of the migration of normal cells with aberrant intrinsic properties in cancer pathophysiology. Aside from these insights, a novel concept termed "oncoprotein metastasis" (OPM) has recently been advanced and proposed to reflect protein-based neoplastic phenomena that might occur even before any modifications relating to the morphology, location or (epi)genetic outfit of cells during the malignant process. Here, evidence is presented that supports the OPM perception and thus should contribute not only to further rethink the definition of a normal cell, but also the treatment of cancer disease in the years to come.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-10069535, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-10623576, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-10938588, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-10995795, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-12526785, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-12526791, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-12951836, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-1339481, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-1412705, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-15057811, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-15680767, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-16813730, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-17429397, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-176594, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-18268316, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-18369415, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-18452160, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-18555776, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-18719284, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-18755941, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-19122629, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-19308067, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-19546858, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-19688775, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-19815521, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-20026604, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-20094047, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-2161368, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-3479684, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-6290023, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-6633649, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-7519375, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-7566179, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-7595130, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-7776899, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-7812921, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-7923156, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-7991544, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-8144628, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-8939849, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-8953032, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-9164814, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-959840, http://linkedlifedata.com/resource/pubmed/commentcorrection/20380702-9739414
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1756-9966
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
30
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Oncoprotein metastasis and its suppression revisited.
pubmed:affiliation
Molecular Concepts Research, Muenster, Germany. ratura@gmx.net
pubmed:publicationType
Journal Article, Review