Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2010-10-11
pubmed:abstractText
We have developed three-dimensional electrospun microfibrous meshes of a novel star branched three-arm poly(?-caprolactone) (*PCL) as potential scaffolds for tissue engineering applications. The processing conditions required to obtain uniform fibers were optimized by studying their influence on fiber morphology and size. Polymer molecular weight and solution feed rate influenced both the mesh microstructure and the tensile properties of the developed mats. Electrospun samples were also tested for their mechanical properties in wet conditions, showing higher yield strength and strain in comparison to that observed in dry conditions. Cell culture experiments employing MC3T3-E1 osteoblast like cells showed good cell viability adhesion and collagen production on the *PCL scaffolds.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1616-5195
pubmed:author
pubmed:issnType
Electronic
pubmed:day
11
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
887-97
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Development of electrospun three-arm star poly(?-caprolactone) meshes for tissue engineering applications.
pubmed:affiliation
Laboratory of Bioactive Polymeric Materials for Biomedical and Environmental Applications (BIOlab), via Vecchia Livornese 1291, 56010 San Piero a Grado (Pi), Department of Chemistry and Industrial Chemistry University of Pisa, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't