Source:http://linkedlifedata.com/resource/pubmed/id/20370621
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2010-4-7
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pubmed:abstractText |
As the breadth and number of bacterial pathogens exhibiting antibiotic resistance is rapidly increasing, our ability to treat new and re-emerging infectious diseases is being threatened. Therefore, the development of new therapeutic strategies, including drugs acting on new targets, is required. In this review, the feasibility of gram-negative bacterial secretion systems for the development of anti-virulence agents and possible arenas for their utility in therapeutic intervention of gram-negative bacterial infections such as gastroenteritis, nosocomial infections, and venereal diseases are discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1040-8401
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
69-77
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pubmed:meshHeading |
pubmed-meshheading:20370621-Antibiotic Prophylaxis,
pubmed-meshheading:20370621-Bacterial Proteins,
pubmed-meshheading:20370621-Communicable Disease Control,
pubmed-meshheading:20370621-Communicable Diseases,
pubmed-meshheading:20370621-Gram-Negative Bacteria,
pubmed-meshheading:20370621-Humans,
pubmed-meshheading:20370621-Virulence Factors
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pubmed:year |
2010
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pubmed:articleTitle |
Prospects for the development and use of gram-negative bacterial virulence protein secretion inhibitors for prophylaxis and treatment of infectious diseases.
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pubmed:affiliation |
Department of Microbiology, University of Washington, Seattle, Washington 98195, USA. hrb@u.washington.edu.
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pubmed:publicationType |
Journal Article,
Review
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