Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2010-4-21
pubmed:abstractText
Free milk oligosaccharides (OS) are major components of mammalian milk. Swine are important agricultural species and biomedical models. Despite their importance, little is known of the OS profile of porcine milk. Herein, the porcine milk glycome was elucidated and monitored over the entire lactation period by liquid chromatography profiling and structural determination with mass spectrometry. Milk was collected from second-parity sows (n = 3) at farrowing and on days 1, 4, 7, and 24 of lactation. Twenty-nine distinct porcine milk oligosaccharides (pMO) were identified. The pMO are highly sialylated, which is more similar to bovine milk than human milk OS. Six fucosylated pMO were detected at low levels in porcine milk, making it more similar to human milk than bovine milk. In general, the pMO content was highest in milk collected at farrowing and day 1 of lactation, decreased during early lactation, but then rose at day 24; however, the pMO displayed different patterns of variation across lactation. In summary, porcine milk contains both acidic (sialylated) and neutral OS, but sialic acid containing OS predominate throughout lactation.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-10632968, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-10837303, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-10940350, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-11253817, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-11270179, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-11755034, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-11787698, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-12562767, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-12741556, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-14638628, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-15384621, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-15583750, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-16011458, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-16214760, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-16575520, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-16751577, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-16882802, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-17002410, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-17284758, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-17915960, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-17966141, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-18088092, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-18183941, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-18203909, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-18322557, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-18832198, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-19028867, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-19109595, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-7284292, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-7931336, http://linkedlifedata.com/resource/pubmed/commentcorrection/20369835-9417989
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1520-5118
pubmed:author
pubmed:issnType
Electronic
pubmed:day
28
pubmed:volume
58
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
4653-9
pubmed:dateRevised
2011-7-28
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Structural determination and daily variations of porcine milk oligosaccharides.
pubmed:affiliation
Department of Chemistry and Biochemistry (School of Medicine), University of California, Davis, California 95616, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural