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pubmed:abstractText |
Avian beta-defensins (AvBDs) represent a group of innate immune genes with broad antimicrobial activity. Within the chicken genome, previous work identified 14 AvBDs in a cluster on chromosome three. The release of a second bird genome, the zebra finch, allows us to study the comparative evolutionary history of these gene clusters between from two species that shared a common ancestor about 100 million years ago.
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pubmed:affiliation |
Edward Grey Institute, Department of Zoology, South Parks Road, Oxford, OX1 3PS, UK. olof.hellgren@zooekol.lu.se
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