Linked Life Data

20357688

Source:http://linkedlifedata.com/resource/pubmed/id/20357688

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2010-4-16
pubmed:abstractText
The degree at which individuals maintain behavioral strategies during uncertain conditions varies widely; however, the neural bases of these individual differences remain unclear. This study examines the functional connectivity of the orbitofrontal cortex during a decision-making task using functional magnetic resonance imaging. The strength of the functional connectivity observed between the medial orbitofrontal cortex and the nucleus accumbens was determined to be correlated with the number of persistent responses made during the decision-making task. It is proposed that top-down control of the orbitofrontal cortex over the ventral striatum is a critical component underlying individual differences in decision making during uncertain conditions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1473-558X
pubmed:author
pubmed:issnType
Electronic
pubmed:day
12
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
502-6
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Human orbitofrontal-striatum functional connectivity modulates behavioral persistence.
pubmed:affiliation
Department of Psychiatry and Institute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Korea.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't