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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2010-4-27
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pubmed:abstractText |
Recently, to identify potential somatic mutations in genes of epidermal growth factor receptor (EGFR) signaling pathway, MEK1 gene mutation at exon 2 and mutation of the AKT2 (v-akt murine thymoma viral oncogene homologue 2) gene at kinase domain have been reported in non-small cell lung cancer.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/AKT2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/EGFR protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/MAP Kinase Kinase 1,
http://linkedlifedata.com/resource/pubmed/chemical/MAP2K1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/PIK3CA protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylinositol 3-Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-akt,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Epidermal Growth Factor
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1556-1380
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
597-600
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:20354455-Adenocarcinoma,
pubmed-meshheading:20354455-Aged,
pubmed-meshheading:20354455-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:20354455-Carcinoma, Squamous Cell,
pubmed-meshheading:20354455-DNA, Neoplasm,
pubmed-meshheading:20354455-Female,
pubmed-meshheading:20354455-Humans,
pubmed-meshheading:20354455-Japan,
pubmed-meshheading:20354455-Lung Neoplasms,
pubmed-meshheading:20354455-MAP Kinase Kinase 1,
pubmed-meshheading:20354455-Male,
pubmed-meshheading:20354455-Mutation,
pubmed-meshheading:20354455-Phosphatidylinositol 3-Kinases,
pubmed-meshheading:20354455-Polymerase Chain Reaction,
pubmed-meshheading:20354455-Prognosis,
pubmed-meshheading:20354455-Proto-Oncogene Proteins c-akt,
pubmed-meshheading:20354455-Receptor, Epidermal Growth Factor,
pubmed-meshheading:20354455-Retrospective Studies
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pubmed:year |
2010
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pubmed:articleTitle |
MEK1 and AKT2 mutations in Japanese lung cancer.
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pubmed:affiliation |
Department of Oncology, Immunology and Surgery II, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. hisasaki@med.nagoya-cu.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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