Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2010-5-18
pubmed:abstractText
Aerobic (5-day-old cultures) and nonreplicating (dormant) Mycobacterium tuberculosis (5-, 12-, and 19-day-old cultures) bacteria were treated with rifampin (R), moxifloxacin (MX), metronidazole (MZ), amikacin (AK), or capreomycin (CP) for 7, 14, and 21 days. R-MX-MZ-AK and R-MX-MZ-CP killed both aerobic and dormant bacilli in 21 days, as shown by lack of regrowth in solid and liquid media. R-MX-MZ-AK and R-MX-MZ-CP also caused a strong decrease of nonreplicating bacilli in 7 days in a cell-based dormancy model.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1098-6596
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
54
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2712-5
pubmed:dateRevised
2011-3-3
pubmed:meshHeading
pubmed-meshheading:20350948-3T3 Cells, pubmed-meshheading:20350948-Adipocytes, pubmed-meshheading:20350948-Amikacin, pubmed-meshheading:20350948-Animals, pubmed-meshheading:20350948-Antitubercular Agents, pubmed-meshheading:20350948-Aza Compounds, pubmed-meshheading:20350948-Capreomycin, pubmed-meshheading:20350948-Colony Count, Microbial, pubmed-meshheading:20350948-Drug Combinations, pubmed-meshheading:20350948-Drug Resistance, Bacterial, pubmed-meshheading:20350948-Humans, pubmed-meshheading:20350948-Latent Tuberculosis, pubmed-meshheading:20350948-Metronidazole, pubmed-meshheading:20350948-Mice, pubmed-meshheading:20350948-Microbial Sensitivity Tests, pubmed-meshheading:20350948-Models, Biological, pubmed-meshheading:20350948-Mycobacterium tuberculosis, pubmed-meshheading:20350948-Quinolines, pubmed-meshheading:20350948-Rifampin
pubmed:year
2010
pubmed:articleTitle
Activity of drug combinations against dormant Mycobacterium tuberculosis.
pubmed:affiliation
Dipartimento di Malattie Infettive, Parassitarie e Immunomediate, Istituto Superiore di Sanità, Viale Regina Elena, Rome, Italy.
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't