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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1991-6-26
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pubmed:databankReference |
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pubmed:abstractText |
Previous transgenic work demonstrated transforming activity of the human T-cell leukemia virus type I Tax protein in fibroblasts. In the present study, a Thy-1-based vector was used to express Tax in thymocytes. These mice developed no functional or neoplastic abnormalities of T cells but developed fibroblastic tumors with a longer latency than in the previous model.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-14946508,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-2536259,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-2688429,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-2866324,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-2868059,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-2871307,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-2873395,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-2881513,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-2886226,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-2888190,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-2888191,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-2894813,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-2896300,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-2917802,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-3046741,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-3057449,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-4108877,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-5919594,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-6177036,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-6261256,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-6760397,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-6951204,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-6979048,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2033674-7031654
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0022-538X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3349-53
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:2033674-Animals,
pubmed-meshheading:2033674-Base Sequence,
pubmed-meshheading:2033674-Gene Expression,
pubmed-meshheading:2033674-Genes, pX,
pubmed-meshheading:2033674-Human T-lymphotropic virus 1,
pubmed-meshheading:2033674-Mice,
pubmed-meshheading:2033674-Mice, Transgenic,
pubmed-meshheading:2033674-Molecular Sequence Data,
pubmed-meshheading:2033674-Promoter Regions, Genetic,
pubmed-meshheading:2033674-Repetitive Sequences, Nucleic Acid,
pubmed-meshheading:2033674-T-Lymphocytes,
pubmed-meshheading:2033674-Transformation, Genetic,
pubmed-meshheading:2033674-Tumor Cells, Cultured
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pubmed:year |
1991
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pubmed:articleTitle |
Transgenic thymocytes are refractory to transformation by the human T-cell leukemia virus type I tax gene.
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pubmed:affiliation |
Department of Neuropharmacology, Research Institute of Scripps Clinic, La Jolla, California 92037.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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