Linked Life Data

20298151

Source:http://linkedlifedata.com/resource/pubmed/id/20298151

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2010-4-19
pubmed:abstractText
Current therapeutic options for patients with progressive thyroid cancer are relatively ineffective. There is a clear need to develop new alternatives for the management of this malignancy. As the knowledge of thyroid cancer biology advances, a large number of genetic events, molecular abnormalities, alterations of signaling pathways have been identified in the development and progression of thyroid neoplasms, and the potential exists to develop compounds targeted to treat thyroid cancers that do not respond to traditional therapy. In this review we described the recent development in thyroid carcinogenesis where the potential and novel intervention may exist. The discussion of thyroid carcinogenesis was integrated with exploitation of anti-thyroid agents that are currently either in clinical trials or in preclinical development for thyroid cancer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1873-5592
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
716-32
pubmed:dateRevised
2010-12-20
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Carcinogenesis and therapeutic strategies in thyroid cancer.
pubmed:affiliation
Department of Biochemistry and Molecular Biology, The School of Basic Medical Sciences, Chongqing Medical University, Chongqing, China. liuzm9999@yahoo.com.cn
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't