Source:http://linkedlifedata.com/resource/pubmed/id/20231819
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2010-4-9
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pubmed:abstractText |
Plant diseases cause massive losses in agriculture. Increasing the natural defenses of plants may reduce the impact of phytopathogens on agricultural productivity. Pattern-recognition receptors (PRRs) detect microbes by recognizing conserved pathogen-associated molecular patterns (PAMPs). Although the overall importance of PAMP-triggered immunity for plant defense is established, it has not been used to confer disease resistance in crops. We report that activity of a PRR is retained after its transfer between two plant families. Expression of EFR (ref. 4), a PRR from the cruciferous plant Arabidopsis thaliana, confers responsiveness to bacterial elongation factor Tu in the solanaceous plants Nicotiana benthamiana and tomato (Solanum lycopersicum), making them more resistant to a range of phytopathogenic bacteria from different genera. Our results in controlled laboratory conditions suggest that heterologous expression of PAMP recognition systems could be used to engineer broad-spectrum disease resistance to important bacterial pathogens, potentially enabling more durable and sustainable resistance in the field.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1546-1696
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pubmed:author |
pubmed-author:DahlbeckDouglasD,
pubmed-author:JonesJonathan D GJD,
pubmed-author:LacombeSéverineS,
pubmed-author:PeetersNemoN,
pubmed-author:RallapalliGhanasyamG,
pubmed-author:Rougon-CardosoAlejandraA,
pubmed-author:SherwoodEmmaE,
pubmed-author:SmokerMatthewM,
pubmed-author:StaskawiczBrianB,
pubmed-author:ThommaBart P H JBP,
pubmed-author:ZipfelCyrilC,
pubmed-author:van EsseH PeterHP
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pubmed:issnType |
Electronic
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
365-9
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pubmed:dateRevised |
2010-11-15
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pubmed:meshHeading | |
pubmed:year |
2010
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pubmed:articleTitle |
Interfamily transfer of a plant pattern-recognition receptor confers broad-spectrum bacterial resistance.
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pubmed:publicationType |
Letter,
Research Support, Non-U.S. Gov't
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