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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2010-3-26
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pubmed:abstractText |
Direct asymmetric aldol reactions of aldehydes with ketones in the presence of a catalytic amount of fluorous sulfonamide 4 and trifluoroacetic acid result in the corresponding aldol products in high yields with up to 96% ee. The fluorous organocatalyst 4 can be readily recovered from the reaction mixture by fluorous solid-phase extraction and could be reused without a significant loss of the catalytic activity and enantioselectivity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1523-7052
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
2
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1620-3
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pubmed:meshHeading |
pubmed-meshheading:20210332-Alcohols,
pubmed-meshheading:20210332-Aldehydes,
pubmed-meshheading:20210332-Catalysis,
pubmed-meshheading:20210332-Cyclization,
pubmed-meshheading:20210332-Hydrocarbons, Fluorinated,
pubmed-meshheading:20210332-Ketones,
pubmed-meshheading:20210332-Molecular Structure,
pubmed-meshheading:20210332-Solid Phase Extraction,
pubmed-meshheading:20210332-Stereoisomerism,
pubmed-meshheading:20210332-Sulfonamides
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pubmed:year |
2010
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pubmed:articleTitle |
Direct asymmetric aldol reaction with recyclable fluorous organocatalyst.
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pubmed:affiliation |
Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu, 501-1196, Japan. miura@gifu-pu.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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