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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2010-3-29
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|
pubmed:abstractText |
The EGFR [epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)] gene is known to harbor genomic alterations in advanced lung cancer involving gene amplification and kinase mutations that predict the clinical response to EGFR-targeted inhibitors. Methods for detecting such molecular changes in lung cancer tumors are desirable.
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pubmed:grant |
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Apr
|
|
pubmed:issn |
1530-8561
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|
pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
56
|
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
623-32
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pubmed:meshHeading |
pubmed-meshheading:20207772-Adult,
pubmed-meshheading:20207772-Aged,
pubmed-meshheading:20207772-Aged, 80 and over,
pubmed-meshheading:20207772-Alleles,
pubmed-meshheading:20207772-DNA, Neoplasm,
pubmed-meshheading:20207772-DNA Mutational Analysis,
pubmed-meshheading:20207772-Disease Progression,
pubmed-meshheading:20207772-Female,
pubmed-meshheading:20207772-Genome, Human,
pubmed-meshheading:20207772-Genotype,
pubmed-meshheading:20207772-Humans,
pubmed-meshheading:20207772-Lung Neoplasms,
pubmed-meshheading:20207772-Male,
pubmed-meshheading:20207772-Middle Aged,
pubmed-meshheading:20207772-Mutation,
pubmed-meshheading:20207772-Neoplasm Staging,
pubmed-meshheading:20207772-Polymerase Chain Reaction,
pubmed-meshheading:20207772-Predictive Value of Tests,
pubmed-meshheading:20207772-Receptor, Epidermal Growth Factor,
pubmed-meshheading:20207772-Tumor Cells, Cultured
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pubmed:year |
2010
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|
pubmed:articleTitle |
Quantifying EGFR alterations in the lung cancer genome with nanofluidic digital PCR arrays.
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pubmed:affiliation |
Fluidigm Corporation, South San Francisco, CA, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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