Source:http://linkedlifedata.com/resource/pubmed/id/20206987
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9725
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pubmed:dateCreated |
2010-5-3
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pubmed:abstractText |
Meticillin-resistant Staphylococcus aureus (MRSA) is endemic in hospitals worldwide, and causes substantial morbidity and mortality. Health-care-associated MRSA infections arise in individuals with predisposing risk factors, such as surgery or presence of an indwelling medical device. By contrast, many community-associated MRSA (CA-MRSA) infections arise in otherwise healthy individuals who do not have such risk factors. Additionally, CA-MRSA infections are epidemic in some countries. These features suggest that CA-MRSA strains are more virulent and transmissible than are traditional hospital-associated MRSA strains. The restricted treatment options for CA-MRSA infections compound the effect of enhanced virulence and transmission. Although progress has been made towards understanding emergence of CA-MRSA, virulence, and treatment of infections, our knowledge remains incomplete. Here we review the most up-to-date knowledge and provide a perspective for the future prophylaxis or new treatments for CA-MRSA infections.
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pubmed:grant | |
pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Bacterial Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Bacterial Toxins,
http://linkedlifedata.com/resource/pubmed/chemical/Exotoxins,
http://linkedlifedata.com/resource/pubmed/chemical/Leukocidins,
http://linkedlifedata.com/resource/pubmed/chemical/Panton-Valentine leukocidin
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1474-547X
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2010 Elsevier Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
375
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1557-68
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pubmed:dateRevised |
2010-9-8
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pubmed:meshHeading |
pubmed-meshheading:20206987-Anti-Bacterial Agents,
pubmed-meshheading:20206987-Bacterial Toxins,
pubmed-meshheading:20206987-Community-Acquired Infections,
pubmed-meshheading:20206987-Drainage,
pubmed-meshheading:20206987-Exotoxins,
pubmed-meshheading:20206987-Humans,
pubmed-meshheading:20206987-Leukocidins,
pubmed-meshheading:20206987-Methicillin-Resistant Staphylococcus aureus,
pubmed-meshheading:20206987-Nasal Cavity,
pubmed-meshheading:20206987-Staphylococcal Infections
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pubmed:year |
2010
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pubmed:articleTitle |
Community-associated meticillin-resistant Staphylococcus aureus.
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pubmed:affiliation |
Laboratory of Human Bacterial Pathogenesis, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA. fdeleo@niaid.nih.gov
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pubmed:publicationType |
Journal Article,
Review,
Research Support, N.I.H., Extramural,
Research Support, N.I.H., Intramural
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