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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2011-1-14
pubmed:abstractText
Recent publications in Japan suggest that Cd in river beds and locally harvested rice tend to be higher in seven prefectures in the north-eastern part on the coast of the Sea of Japan (the high-Cd zone). The present study was initiated to investigate the current level of exposure to Cd and possible health effects among local populations in the zone. Thus, levels of Cd and three tubular dysfunction markers [i.e., ?(1)-MG, ?(2)-MG, and N-acetyl-?-D-glucosaminidase (NAG)] were examined in urine of local residents (700 and 704 adult women, respectively) in two prefectures (prefecture 1 and prefecture 7), which were located in the north-east (prefecture 1) and south-west ends (prefecture 7) of the high-Cd zone. Urinary Cd levels [e.g., 0.99 and 0.78 ?g/l as geometric mean (GM) for observed (non-corrected) values, respectively] in prefecture 1 and prefecture 7 were comparable to the levels in other parts of Japan (All Japan-A; 0.99 ?g/l). Correspondingly, GM values for ?(1)-MG (2.29 and 1.99 mg/l vs. 2.17 mg/l for All Japan-A) and for ?(2)-MG (87 and 80 ?g/l vs. 99 ?g/l for All Japan-A) were not elevated, and NAG also stayed unchanged (2.89 and 2.87 units/l for prefecture 1 and prefecture 7, respectively). Evaluation in combination with the findings in other five prefectures in the zone suggests that Cd exposure is equal to the national average both in prefecture 1 and in prefecture 7, whereas Cd exposure appeared to be elevated in the central part of the zone. The observation appears to be on line with geographical location of the two prefectures that they are on the two ends of the zone of high natural Cd background.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1559-0720
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
139
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
217-27
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Low cadmium levels in urine of residents in two prefectures where cadmium levels in locally harvested brown rice are higher than in other prefectures in Japan.
pubmed:affiliation
Kyoto Industrial Health Association (Main Office), 67 Nishinokyo-Kitatsuboicho, Nakagyo-ku, Kyoto 804-8472, Japan. ikeda@hokenkai.or.jp
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't