Linked Life Data

20158988

Source:http://linkedlifedata.com/resource/pubmed/id/20158988

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2010-2-17
pubmed:abstractText
The G protein-coupled receptor gene GPR3 is expressed predominantly in oocytes, and functions in the early development of oocytes in the ovarian follicle. GPR3 is essential for meiotic arrest maintenance in mice, which makes it a candidate gene for premature ovarian failure (POF). The coding region of GPR3 was screened in 100 Chinese POF patients for variants of the GPR3 gene. Except for one novel variant in the 3'UTR region in three subjects and another novel synonymous c.135G-->A variant in one subject, no perturbations were found in the coding region. The results of this study suggested that mutations in GPR3 are not a common cause of POF in Chinese women.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1472-6491
pubmed:author
pubmed:copyrightInfo
Copyright (c) 2009 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
53-5
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
GPR3 may not be a potential candidate gene for premature ovarian failure.
pubmed:affiliation
Graduate School, Peking Union Medical College, Beijing 100730, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't