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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2010-3-15
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pubmed:abstractText |
Complex I (CI) deficiency is the most frequent cause of OXPHOS disorders. Recent studies have shown increases in reactive oxygen species (ROS) production and mitochondrial network disturbances in patients' fibroblasts harbouring mutations in CI subunits.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0006-3002
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2010 Elsevier B.V. All rights reserved.
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pubmed:issnType |
Print
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pubmed:volume |
1802
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
443-53
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pubmed:meshHeading |
pubmed-meshheading:20153825-Acidosis,
pubmed-meshheading:20153825-Adenosine Triphosphate,
pubmed-meshheading:20153825-Blotting, Western,
pubmed-meshheading:20153825-Cells, Cultured,
pubmed-meshheading:20153825-Electron Transport Complex I,
pubmed-meshheading:20153825-Energy Metabolism,
pubmed-meshheading:20153825-Epilepsy,
pubmed-meshheading:20153825-Fibroblasts,
pubmed-meshheading:20153825-Flow Cytometry,
pubmed-meshheading:20153825-Fluorescent Antibody Technique,
pubmed-meshheading:20153825-Glycolysis,
pubmed-meshheading:20153825-Humans,
pubmed-meshheading:20153825-Infant,
pubmed-meshheading:20153825-Leukoencephalopathies,
pubmed-meshheading:20153825-Male,
pubmed-meshheading:20153825-Mitochondria,
pubmed-meshheading:20153825-Mitochondrial Diseases,
pubmed-meshheading:20153825-Mutation,
pubmed-meshheading:20153825-NADH Dehydrogenase,
pubmed-meshheading:20153825-Oxygen Consumption,
pubmed-meshheading:20153825-RNA, Messenger,
pubmed-meshheading:20153825-Reactive Oxygen Species,
pubmed-meshheading:20153825-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20153825-Skin
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pubmed:year |
2010
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pubmed:articleTitle |
Mitochondrial bioenergetics and dynamics interplay in complex I-deficient fibroblasts.
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pubmed:affiliation |
Centro de Investigación, Hospital Universitario 12 de Octubre, Madrid, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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