rdf:type |
|
lifeskim:mentions |
umls-concept:C0012854,
umls-concept:C0019682,
umls-concept:C0019699,
umls-concept:C0019704,
umls-concept:C0030705,
umls-concept:C0032105,
umls-concept:C0205210,
umls-concept:C0242732,
umls-concept:C0243076,
umls-concept:C0332281,
umls-concept:C0376705,
umls-concept:C1332700,
umls-concept:C1521761,
umls-concept:C1524063
|
pubmed:issue |
4
|
pubmed:dateCreated |
2010-3-15
|
pubmed:abstractText |
Most treated HIV-1 patients have undetectable viral loads and the strategies for managing long-term side effects may involve a new class of antiretroviral-like CCR5 antagonists. Tropism determination based on proviral DNA sequence is necessary for patients with a fully suppressed plasma viral load, as assays analysing DNA phenotypes have yet to be developed. We aimed to analyse HIV-1 tropism using proviral DNA sequencing and the associated factors, in a group of patients on antiretroviral (ARV) treatment with an undetectable viral load in plasma.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
1460-2091
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
65
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
749-51
|
pubmed:meshHeading |
pubmed-meshheading:20150182-Anti-HIV Agents,
pubmed-meshheading:20150182-DNA, Viral,
pubmed-meshheading:20150182-HIV Infections,
pubmed-meshheading:20150182-HIV-1,
pubmed-meshheading:20150182-Humans,
pubmed-meshheading:20150182-Proviruses,
pubmed-meshheading:20150182-Receptors, CCR5,
pubmed-meshheading:20150182-Receptors, HIV,
pubmed-meshheading:20150182-Sequence Analysis, DNA,
pubmed-meshheading:20150182-Viral Load,
pubmed-meshheading:20150182-Viral Tropism
|
pubmed:year |
2010
|
pubmed:articleTitle |
Factors associated with proviral DNA HIV-1 tropism in antiretroviral therapy-treated patients with fully suppressed plasma HIV viral load: implications for the clinical use of CCR5 antagonists.
|
pubmed:affiliation |
Université Pierre et Marie Curie-Paris 6, UMR S-943 Paris, F-75013, France. cathia.soulie@psl.aphp.fr
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|