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rdf:type |
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lifeskim:mentions |
umls-concept:C0011155,
umls-concept:C0017262,
umls-concept:C0023821,
umls-concept:C0024432,
umls-concept:C0026809,
umls-concept:C0162638,
umls-concept:C0185117,
umls-concept:C0332281,
umls-concept:C0392756,
umls-concept:C0524828,
umls-concept:C1121571,
umls-concept:C1413218,
umls-concept:C1517945,
umls-concept:C2911684
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pubmed:issue |
1
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|
pubmed:dateCreated |
2010-7-12
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|
pubmed:abstractText |
Paraoxonase 1 (PON1) was shown to stimulate HDL binding and HDL-mediated cholesterol efflux from macrophages. This study examined the role of PON1 in the expression of proteins that enhance macrophage HDL binding, i.e. ABCA1 and SR-BI.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1879-1484
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pubmed:author |
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pubmed:copyrightInfo |
Copyright (c) 2010 Elsevier Ireland Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
211
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
61-8
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pubmed:meshHeading |
pubmed-meshheading:20149374-Animals,
pubmed-meshheading:20149374-Apoptosis,
pubmed-meshheading:20149374-Aryldialkylphosphatase,
pubmed-meshheading:20149374-Cell Line,
pubmed-meshheading:20149374-Humans,
pubmed-meshheading:20149374-Lipoproteins, HDL,
pubmed-meshheading:20149374-Lysophosphatidylcholines,
pubmed-meshheading:20149374-Macrophages,
pubmed-meshheading:20149374-Mice,
pubmed-meshheading:20149374-Mice, Inbred C57BL,
pubmed-meshheading:20149374-Scavenger Receptors, Class B,
pubmed-meshheading:20149374-Up-Regulation
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pubmed:year |
2010
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pubmed:articleTitle |
Paraoxonase 1 (PON1) deficiency in mice is associated with reduced expression of macrophage SR-BI and consequently the loss of HDL cytoprotection against apoptosis.
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pubmed:affiliation |
The Lipid Research Laboratory, Technion Faculty of Medicine, The Rappaport Family Institute for Research in the Medical Sciences, and Rambam Medical Center, 31096 Haifa, Israel. Fuhrman@tx.technion.ac.il
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pubmed:publicationType |
Journal Article
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