rdf:type |
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lifeskim:mentions |
|
pubmed:issue |
5
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pubmed:dateCreated |
2010-2-22
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pubmed:abstractText |
By use of the model virus, expressing the HCV envelope proteins E1 and E2, bioassay guided separation of the MeOH extract from Rosa rugosa Thunb. disclosed tellimagrandin I (1) together with eugeniin (2) and casuarictin (3) as the potent HCV invasion inhibitors. Furthermore, structure-activity relationship analysis of some relative tannins including the synthesized analogs elucidated the partial structures crucial for potent activity of 1.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antiviral Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Biphenyl Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/E1 protein, Hepatitis C virus,
http://linkedlifedata.com/resource/pubmed/chemical/Gallic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Glucosides,
http://linkedlifedata.com/resource/pubmed/chemical/Viral Envelope Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/casuarictin,
http://linkedlifedata.com/resource/pubmed/chemical/eugeniin,
http://linkedlifedata.com/resource/pubmed/chemical/glycoprotein E2, Hepatitis C virus,
http://linkedlifedata.com/resource/pubmed/chemical/tellimagrandin I
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
|
pubmed:issn |
1464-3405
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pubmed:author |
|
pubmed:copyrightInfo |
Copyright 2010 Elsevier Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
20
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1598-600
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pubmed:meshHeading |
|
pubmed:year |
2010
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pubmed:articleTitle |
Tellimagrandin I, HCV invasion inhibitor from Rosae Rugosae Flos.
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pubmed:affiliation |
Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka Suita, Osaka 565-0871, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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