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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2010-2-10
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pubmed:abstractText |
Microneedle-mediated drug delivery is a promising method for transdermal delivery of insulin, incretin mimetics, and other protein-based pharmacologic agents for treatment of diabetes mellitus. One factor that has limited clinical application of conventional microneedle technology is the poor fracture behavior of microneedles that are created using conventional materials and methods. In this study polymer microneedles for transdermal delivery were created using a two-photon polymerization (2PP) microfabrication and subsequent polydimethylsiloxane (PDMS) micromolding process.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20144361-11159258,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20144361-11694019,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20144361-12046705,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20144361-12659425,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20144361-14623977,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20144361-15040576,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20144361-15090063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20144361-15212158,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20144361-15212920,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20144361-15866334,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20144361-16556569,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20144361-16701886,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20144361-16720698,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20144361-17286288,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20144361-17387600,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20144361-18563579,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20144361-18716497
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1932-2968
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pubmed:author |
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pubmed:copyrightInfo |
(c) 2009 Diabetes Technology Society.
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pubmed:issnType |
Electronic
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
304-11
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20144361-Administration, Cutaneous,
pubmed-meshheading:20144361-Biocompatible Materials,
pubmed-meshheading:20144361-Diabetes Mellitus,
pubmed-meshheading:20144361-Dimethylpolysiloxanes,
pubmed-meshheading:20144361-Drug Delivery Systems,
pubmed-meshheading:20144361-Humans,
pubmed-meshheading:20144361-Insulin,
pubmed-meshheading:20144361-Microtechnology,
pubmed-meshheading:20144361-Needles,
pubmed-meshheading:20144361-Polymethacrylic Acids
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pubmed:year |
2009
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pubmed:articleTitle |
Fabrication of polymer microneedles using a two-photon polymerization and micromolding process.
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pubmed:affiliation |
Joint Department of Biomedical Engineering, University of North Carolina and North Carolina State University, Raleigh, North Carolina, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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