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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2011-4-15
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pubmed:abstractText |
Quinolone and ?-lactam resistance mechanisms and clonal relationships were characterized among Escherichia coli isolates resistant to ciprofloxacin and extended-spectrum cephalosporins associated with human extra-intestinal infections in Rome. The E. coli. ST131 clone was found to be prevalent. This clone invariably carried a specific pattern of substitutions in the topoisomerase genes and all isolates but one produced CTX-M-15. One ST131 isolate produced SHV-12. The new ST131 variant described here is of particular concern because it combines fluoroquinolone resistance and chromosomally encoded CTX-M-15.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1469-0691
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pubmed:author |
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pubmed:copyrightInfo |
© 2010 The Authors. Journal Compilation © 2010 European Society of Clinical Microbiology and Infectious Diseases.
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pubmed:issnType |
Electronic
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1555-8
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pubmed:meshHeading |
pubmed-meshheading:20121822-Amino Acid Substitution,
pubmed-meshheading:20121822-Anti-Bacterial Agents,
pubmed-meshheading:20121822-Bacterial Typing Techniques,
pubmed-meshheading:20121822-Ciprofloxacin,
pubmed-meshheading:20121822-Cluster Analysis,
pubmed-meshheading:20121822-DNA Topoisomerase IV,
pubmed-meshheading:20121822-Drug Resistance, Multiple, Bacterial,
pubmed-meshheading:20121822-Escherichia coli,
pubmed-meshheading:20121822-Escherichia coli Infections,
pubmed-meshheading:20121822-Humans,
pubmed-meshheading:20121822-Microbial Sensitivity Tests,
pubmed-meshheading:20121822-Molecular Epidemiology,
pubmed-meshheading:20121822-Molecular Typing,
pubmed-meshheading:20121822-Mutation, Missense,
pubmed-meshheading:20121822-Rome,
pubmed-meshheading:20121822-beta-Lactamases
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pubmed:year |
2010
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pubmed:articleTitle |
Ciprofloxacin-resistant, CTX-M-15-producing Escherichia coli ST131 clone in extraintestinal infections in Italy.
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pubmed:affiliation |
Department of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, Rome, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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