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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-3-22
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pubmed:abstractText |
The conventional treatment protocol in high-intensity focused ultrasound (HIFU) therapy utilizes a dense-scan strategy to produce closely packed thermal lesions aiming at eradicating as much tumor mass as possible. However, this strategy is not most effective in terms of inducing a systemic anti-tumor immunity so that it cannot provide efficient micro-metastatic control and long-term tumor resistance. We have previously provided evidence that HIFU may enhance systemic anti-tumor immunity by in situ activation of dendritic cells (DCs) inside HIFU-treated tumor tissue. The present study was conducted to test the feasibility of a sparse-scan strategy to boost HIFU-induced anti-tumor immune response by more effectively promoting DC maturation.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-10099162,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-10889823,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-11123353,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-11274554,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-12563297,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-12667339,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-12756090,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-14622488,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-14666382,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-14716736,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-14740176,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-14998677,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-15047409,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-15081972,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-15546396,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-15550325,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-16055092,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-16365396,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-17625013,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-17854983,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-18007663,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-19276179,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-19287104,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-8059487,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-8665590,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20105334-9521319
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1479-5876
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
7
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pubmed:dateRevised |
2010-9-27
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pubmed:meshHeading |
pubmed-meshheading:20105334-Animals,
pubmed-meshheading:20105334-Cell Line, Tumor,
pubmed-meshheading:20105334-Dendritic Cells,
pubmed-meshheading:20105334-Female,
pubmed-meshheading:20105334-Flow Cytometry,
pubmed-meshheading:20105334-Humans,
pubmed-meshheading:20105334-Immunity,
pubmed-meshheading:20105334-Mice,
pubmed-meshheading:20105334-Mice, Inbred C57BL,
pubmed-meshheading:20105334-Neoplasm Transplantation,
pubmed-meshheading:20105334-Neoplasms, Experimental,
pubmed-meshheading:20105334-Temperature,
pubmed-meshheading:20105334-Ultrasonic Therapy
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pubmed:year |
2010
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pubmed:articleTitle |
Boosting high-intensity focused ultrasound-induced anti-tumor immunity using a sparse-scan strategy that can more effectively promote dendritic cell maturation.
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pubmed:affiliation |
Department of Biochemical Pharmacy, School of Pharmacy, Second Military Medical University, Shanghai 200433, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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