Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2010-9-29
pubmed:abstractText
Nonlinear optical microscopy (NLOM) was applied for monitoring dermal wound healing after mesenchymal stem cell (MSC) transplantation. Our results showed that NLOM can reveal different regeneration processes of collagen in nontreated and MSC-treated wound dermis. Specifically, the temporal increases in the intensity of second-harmonic-generation signals can quantify kinetic properties of collagen regeneration. Orientation analysis of collagen fiber bundles can monitor the formation of new normal collagen fiber bundles, which is an indicator for evaluating the therapy response. It was also found that NLOM can track MSCs' location and recruitment. These findings suggested that NLOM is ideal for monitoring the progress of dermal wound healing.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1937-3392
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1107-10
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Monitoring dermal wound healing after mesenchymal stem cell transplantation using nonlinear optical microscopy.
pubmed:affiliation
Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't