pubmed:abstractText |
Comprehensive studies indicate that oltipraz exerts cancer chemopreventive effects. Oltipraz has other therapeutic potentials, which include anti-fibrotic effect, inhibition of insulin resistance, mitochondrial protection and cytoprotective effect against oxidative stress. Although antioxidant mechanisms may account for its cancer chemopreventive effect, details on the molecular mechanism still remain to be clarified.
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pubmed:affiliation |
Seoul National University, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Sillim-dong, Gwanak-gu, Seoul 151-742, Korea, Republic of Korea. sgk@snu.ac.kr
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