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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2010-8-27
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pubmed:abstractText |
von Willebrand disease (VWD) Vicenza is characterized by low plasma von Willebrand factor (VWF) levels, the presence of ultra-large (UL) VWF multimers and less prominent satellite bands on multimer gels, and the heterozygous amino acid substitution R1205H in the VWF gene. The pathogenesis of VWD Vicenza has been elusive. Accelerated clearance is implicated as a cause of low VWF level.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1538-7836
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1273-80
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pubmed:meshHeading |
pubmed-meshheading:20088930-Amino Acid Substitution,
pubmed-meshheading:20088930-Cell Line,
pubmed-meshheading:20088930-Electrophoresis, Agar Gel,
pubmed-meshheading:20088930-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:20088930-Female,
pubmed-meshheading:20088930-Humans,
pubmed-meshheading:20088930-Male,
pubmed-meshheading:20088930-Pedigree,
pubmed-meshheading:20088930-Recombinant Proteins,
pubmed-meshheading:20088930-von Willebrand Diseases,
pubmed-meshheading:20088930-von Willebrand Factor
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pubmed:year |
2010
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pubmed:articleTitle |
Accelerated clearance alone explains ultra-large multimers in von Willebrand disease Vicenza.
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pubmed:affiliation |
Central Immunology Laboratory, Semmelweis University, Budapest, Hungary.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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