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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-2-12
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pubmed:abstractText |
The role of the innate immune protein mannose-binding lectin (MBL) in host defence against severe respiratory infection remains controversial. Thoracic empyema is a suppurative lung infection that arises as a major complication of pneumonia and is associated with a significant mortality. Although the pathogenesis of thoracic empyema is poorly understood, genetic susceptibility loci for this condition have recently been identified. The possible role of MBL genotypic deficiency in susceptibility to thoracic empyema has not previously been reported.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20078874-10199352,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20078874-11255386,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20078874-11530147,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20078874-11530152,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20078874-11986203,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20078874-12047967,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20078874-12223282,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20078874-12227737,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20078874-12387984,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20078874-12914814,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20078874-14593599,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20078874-14614673,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20078874-15148337,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20078874-15745977,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20078874-16642008,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20078874-16840746,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20078874-17463416,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20078874-18582923,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20078874-18611155,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20078874-18641104,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20078874-18729778,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20078874-9154025
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2350
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pubmed:author |
pubmed-author:ChapmanStephen JSJ,
pubmed-author:CrookDerrick WDW,
pubmed-author:DaviesChristopher W HCW,
pubmed-author:DaviesRobert J ORJ,
pubmed-author:DayNicholas PNP,
pubmed-author:HillAdrian V SAV,
pubmed-author:KhorChiea CCC,
pubmed-author:MaskellNicholas ANA,
pubmed-author:MooreCatrin ECE,
pubmed-author:RautanenAnnaA,
pubmed-author:VannbergFredrik OFO
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pubmed:issnType |
Electronic
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5
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pubmed:dateRevised |
2010-9-28
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pubmed:meshHeading |
pubmed-meshheading:20078874-Chi-Square Distribution,
pubmed-meshheading:20078874-Empyema, Pleural,
pubmed-meshheading:20078874-Genetic Association Studies,
pubmed-meshheading:20078874-Genetic Predisposition to Disease,
pubmed-meshheading:20078874-Genotype,
pubmed-meshheading:20078874-Humans,
pubmed-meshheading:20078874-Mannose-Binding Lectin,
pubmed-meshheading:20078874-Polymerase Chain Reaction,
pubmed-meshheading:20078874-Polymorphism, Single Nucleotide
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pubmed:year |
2010
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pubmed:articleTitle |
Mannose-binding lectin genotypes: lack of association with susceptibility to thoracic empyema.
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pubmed:affiliation |
The Wellcome Trust Centre for Human Genetics, University of Oxford, UK. schapman@well.ox.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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