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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2010-1-5
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pubmed:abstractText |
Reported incidences of prostate cancer and masculinization of animals indicate a release of compounds with androgenic properties into the environment. Large numbers of environmental pollutants have been screened to identify such compounds; however, not until recently was 1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane (TBECH) identified as the first potent activator of the human androgen receptor (hAR). TBECH has been found in beluga whales and bird eggs and has also been found to be maternally transferred in zebrafish.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/20049203-10330684,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20049203-10363963,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20049203-10419007,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20049203-10746941,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20049203-11509745,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20049203-12107189,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20049203-12657354,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20049203-12836968,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20049203-14565775,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20049203-14579009,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20049203-15064155,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20049203-1510931,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20049203-15336704,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/20049203-15579329,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/20049203-15950433,
http://linkedlifedata.com/resource/pubmed/commentcorrection/20049203-16107211,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/20049203-9846162
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1552-9924
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
117
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1853-9
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pubmed:dateRevised |
2010-9-28
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pubmed:meshHeading |
pubmed-meshheading:20049203-Cell Line, Tumor,
pubmed-meshheading:20049203-Cyclohexanes,
pubmed-meshheading:20049203-Endocrine Disruptors,
pubmed-meshheading:20049203-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:20049203-Flame Retardants,
pubmed-meshheading:20049203-Hep G2 Cells,
pubmed-meshheading:20049203-Humans,
pubmed-meshheading:20049203-Male,
pubmed-meshheading:20049203-Prostatic Neoplasms,
pubmed-meshheading:20049203-Receptors, Androgen,
pubmed-meshheading:20049203-Stereoisomerism
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pubmed:year |
2009
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pubmed:articleTitle |
Diastereomers of the brominated flame retardant 1,2-dibromo-4-(1,2 dibromoethyl)cyclohexane induce androgen receptor activation in the hepg2 hepatocellular carcinoma cell line and the lncap prostate cancer cell line.
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pubmed:affiliation |
Orebro Life Science Center, Academy of Science and Technology, Orebro University, Orebro, Sweden.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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