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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1991-4-23
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pubmed:abstractText |
Human and rodent genomes contain multiple copies of ferritin H and L subunit sequences, although it is not yet clear whether there is more than one expressed gene for either of these subunits. We have isolated a cDNA corresponding to mouse ferritin H subunit and observed that the mouse genome contains three to four H-related sequences. This cDNA was used to establish the genomic location of mouse ferritin H subunit genes by chromosomal in situ hybridization. Metaphase chromosomes of concanavalin A-stimulated lymphocytes from a WMP male mouse were examined by in situ hybridization with 3H-labeled cDNA and the chromosomes were identified by R banding (fluorochrome-photolysis-Giemsa method). The results indicate that mouse ferritin H-related sequences map at chromosomes 3, 6, and 19. Homology of synteny between human and mouse suggests that the sequence on mouse chromosome 19 corresponds to the structural H gene.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0888-7543
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
204-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2004762-Animals,
pubmed-meshheading:2004762-Cells, Cultured,
pubmed-meshheading:2004762-Chromosome Banding,
pubmed-meshheading:2004762-Chromosome Mapping,
pubmed-meshheading:2004762-Ferritins,
pubmed-meshheading:2004762-Humans,
pubmed-meshheading:2004762-Karyotyping,
pubmed-meshheading:2004762-Male,
pubmed-meshheading:2004762-Mice,
pubmed-meshheading:2004762-Nucleic Acid Hybridization,
pubmed-meshheading:2004762-Sequence Homology, Nucleic Acid
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pubmed:year |
1991
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pubmed:articleTitle |
Mouse ferritin H sequences map to chromosomes 3, 6, and 19.
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pubmed:affiliation |
Laboratoire de Genetique Moleculaire, Faculte X. Bichat, Marseille, France.
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pubmed:publicationType |
Journal Article
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