Linked Life Data

20047161

Source:http://linkedlifedata.com/resource/pubmed/id/20047161

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2010-1-4
pubmed:abstractText
Recent developments in the field of neurophysiology have led to the refinement of neurophysiological techniques, enabling clinical investigators to assess neuropathy patients with greater precision. In addition to conventional nerve conduction studies and electromyography, novel axonal excitability techniques and quantitative sensory testing may be used to improve diagnosis and to characterize and serially monitor peripheral nerve disorders. A significant expansion in the number of clinical trials being conducted for neurological indications has increased the impetus to further develop neurophysiological measures that reflect the responsiveness to drug therapies. Measures such as motor unit number estimation and the neurophysiological index may facilitate the advancement of compounds in the drug discovery pipeline. This review summarizes several electrodiagnostic and neurophysiological techniques, both conventional and novel, highlighting recent advances that are relevant to disease diagnosis and the assessment of patient response to treatment strategies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
2040-3429
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
72-9
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Neurophysiological methodologies: diagnosis of peripheral nerve disease and assessment of pharmacological agents.
pubmed:affiliation
Prince of Wales Medical Research Institute, Barker Street, Randwick, NSW 2031, Australia.
pubmed:publicationType
Journal Article, Review