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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2010-5-13
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pubmed:abstractText |
Patients with chronic renal failure are at high risk of cardiovascular diseases. Previous studies in healthy population showed that hypoadiponectinemia was associated with high cardiovascular disease risk. However, plasma adiponectin (APN) levels are increased in renal dysfunction. Therefore, the clinical significance of plasma APN level in patients with moderate renal dysfunction is controversial. The aim of this study was to determine the change of plasma APN levels in a mouse model of renal failure and the loss of vasculo-protective function of APN in the presence of high cystatin C levels.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adiponectin,
http://linkedlifedata.com/resource/pubmed/chemical/Biological Markers,
http://linkedlifedata.com/resource/pubmed/chemical/CST3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Cell Adhesion Molecules,
http://linkedlifedata.com/resource/pubmed/chemical/Cst3 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Cystatin C,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha,
http://linkedlifedata.com/resource/pubmed/chemical/adiponectin, human,
http://linkedlifedata.com/resource/pubmed/chemical/adiponectin, mouse
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1755-3245
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
86
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
471-7
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pubmed:meshHeading |
pubmed-meshheading:20035033-Adiponectin,
pubmed-meshheading:20035033-Adipose Tissue, White,
pubmed-meshheading:20035033-Animals,
pubmed-meshheading:20035033-Biological Markers,
pubmed-meshheading:20035033-Cell Adhesion Molecules,
pubmed-meshheading:20035033-Cells, Cultured,
pubmed-meshheading:20035033-Cystatin C,
pubmed-meshheading:20035033-Disease Models, Animal,
pubmed-meshheading:20035033-Endothelial Cells,
pubmed-meshheading:20035033-Kidney Failure, Chronic,
pubmed-meshheading:20035033-Male,
pubmed-meshheading:20035033-Metabolic Clearance Rate,
pubmed-meshheading:20035033-Mice,
pubmed-meshheading:20035033-Mice, Inbred C57BL,
pubmed-meshheading:20035033-Mice, Knockout,
pubmed-meshheading:20035033-Nephrectomy,
pubmed-meshheading:20035033-RNA, Messenger,
pubmed-meshheading:20035033-Recombinant Proteins,
pubmed-meshheading:20035033-Time Factors,
pubmed-meshheading:20035033-Tumor Necrosis Factor-alpha,
pubmed-meshheading:20035033-Up-Regulation
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pubmed:year |
2010
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pubmed:articleTitle |
Increment and impairment of adiponectin in renal failure.
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pubmed:affiliation |
Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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