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rdf:type |
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lifeskim:mentions |
umls-concept:C0011306,
umls-concept:C0021083,
umls-concept:C0205369,
umls-concept:C0871261,
umls-concept:C1420737,
umls-concept:C1425141,
umls-concept:C1539967,
umls-concept:C1704632,
umls-concept:C1704675,
umls-concept:C1706817,
umls-concept:C1709059,
umls-concept:C2911692
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pubmed:issue |
8
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pubmed:dateCreated |
2010-7-19
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pubmed:abstractText |
Specific immunotherapy (SIT) is the only curable remedy for allergic disorders currently; however, the underlying mechanism is not fully understood yet. This study aimed to elucidate the mechanism of SIT on suppressing TIM4 (T cell immunoglobulin mucin domain molecule 4) expression in dendritic cells (DCs) and modulating the skewed T helper 2 (Th2) responses in patients with airway allergy.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Dermatophagoides,
http://linkedlifedata.com/resource/pubmed/chemical/Arthropod Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Cysteine Endopeptidases,
http://linkedlifedata.com/resource/pubmed/chemical/Dermatophagoides pteronyssinus...,
http://linkedlifedata.com/resource/pubmed/chemical/FCGR1A protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/HAVCR1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, IgG,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Virus,
http://linkedlifedata.com/resource/pubmed/chemical/TIMD4 protein, human
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1398-9995
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
986-95
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:20028372-Antigens, Dermatophagoides,
pubmed-meshheading:20028372-Arthropod Proteins,
pubmed-meshheading:20028372-Cell Differentiation,
pubmed-meshheading:20028372-Cysteine Endopeptidases,
pubmed-meshheading:20028372-Dendritic Cells,
pubmed-meshheading:20028372-Desensitization, Immunologic,
pubmed-meshheading:20028372-Humans,
pubmed-meshheading:20028372-Hypersensitivity, Immediate,
pubmed-meshheading:20028372-Membrane Glycoproteins,
pubmed-meshheading:20028372-Membrane Proteins,
pubmed-meshheading:20028372-Receptors, IgG,
pubmed-meshheading:20028372-Receptors, Virus,
pubmed-meshheading:20028372-Rhinitis,
pubmed-meshheading:20028372-Th2 Cells
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pubmed:year |
2010
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pubmed:articleTitle |
Specific immunotherapy suppresses Th2 responses via modulating TIM1/TIM4 interaction on dendritic cells.
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pubmed:affiliation |
Department of Otolaryngology, Head and Neck Surgery, the Second Hospital, Shanxi Medical University, Taiyuan, Shanxi, China. fahyj@126.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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