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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2010-1-19
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pubmed:abstractText |
For several chronic inflammatory disease states, therapy is enhanced by improving the pharmacokinetic properties of anti-inflammatory drugs through conjugation with polyethylene glycol. We hypothesized that part of the beneficial action of PEGylated drugs may be derived from the anti-inflammatory properties of polyethylene glycol (PEG) itself.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1530-0293
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
629-36
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pubmed:meshHeading |
pubmed-meshheading:20009757-Animals,
pubmed-meshheading:20009757-Anti-Inflammatory Agents,
pubmed-meshheading:20009757-Cell Line,
pubmed-meshheading:20009757-Cell Survival,
pubmed-meshheading:20009757-Cytokines,
pubmed-meshheading:20009757-Female,
pubmed-meshheading:20009757-Flow Cytometry,
pubmed-meshheading:20009757-Humans,
pubmed-meshheading:20009757-Inflammation,
pubmed-meshheading:20009757-Leukocytes, Mononuclear,
pubmed-meshheading:20009757-Macrophages,
pubmed-meshheading:20009757-Male,
pubmed-meshheading:20009757-Mice,
pubmed-meshheading:20009757-Mice, Inbred C57BL,
pubmed-meshheading:20009757-Neutrophils,
pubmed-meshheading:20009757-Polyethylene Glycols,
pubmed-meshheading:20009757-Rats,
pubmed-meshheading:20009757-Rats, Wistar,
pubmed-meshheading:20009757-Sepsis,
pubmed-meshheading:20009757-Stroke Volume
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pubmed:year |
2010
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pubmed:articleTitle |
Low-molecular-weight polyethylene glycol improves survival in experimental sepsis.
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pubmed:affiliation |
Centre for Anaesthesia, Critical Care and Pain Management, University College London, London, UK. g.ackland@ucl.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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