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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2010-2-1
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pubmed:abstractText |
We reformulated a multiplex PCR algorithm for serotyping of pneumococcal meningitis directly on cerebrospinal fluid (CSF). Compared to established methods on isolates, CSF-based PCR had at least 80% sensitivity and 100% specificity. In regional meningitis surveillance, CSF-based PCR increased the serotype information yield from 40% of cases (isolate testing) to 90%.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1098-660X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
612-4
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pubmed:dateRevised |
2010-9-28
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pubmed:meshHeading |
pubmed-meshheading:20007384-Africa,
pubmed-meshheading:20007384-Bacterial Typing Techniques,
pubmed-meshheading:20007384-Cerebrospinal Fluid,
pubmed-meshheading:20007384-Genotype,
pubmed-meshheading:20007384-Humans,
pubmed-meshheading:20007384-Meningitis, Pneumococcal,
pubmed-meshheading:20007384-Polymerase Chain Reaction,
pubmed-meshheading:20007384-Sensitivity and Specificity,
pubmed-meshheading:20007384-Serotyping,
pubmed-meshheading:20007384-Streptococcus pneumoniae
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pubmed:year |
2010
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pubmed:articleTitle |
Serotyping pneumococcal meningitis cases in the African meningitis belt by use of multiplex PCR with cerebrospinal fluid.
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pubmed:affiliation |
Agence de Médecine Préventive, at the Institut Pasteur, 25-28 Rue du Dr. Roux, 75724 Paris Cedex 15, France.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Evaluation Studies
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