Source:http://linkedlifedata.com/resource/pubmed/id/20003451
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
2010-1-27
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| pubmed:abstractText |
Tumor necrosis factor is a pleiotropic cytokine with potent immune regulatory functions. Although tumor necrosis factor inhibitors have demonstrated great utility in treating other autoimmune diseases, such as rheumatoid arthritis, there are conflicting results in Sjögren's syndrome. The aim of this study was to assess the effect of a locally expressed tumor necrosis factor inhibitor on the salivary gland function and histopathology in an animal model of Sjögren's syndrome.
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| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
1478-6362
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| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:volume |
11
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
R189
|
| pubmed:dateRevised |
2011-1-10
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| pubmed:meshHeading |
pubmed-meshheading:20003451-Animals,
pubmed-meshheading:20003451-Cytokines,
pubmed-meshheading:20003451-Disease Models, Animal,
pubmed-meshheading:20003451-Female,
pubmed-meshheading:20003451-Gene Therapy,
pubmed-meshheading:20003451-Gene Transfer Techniques,
pubmed-meshheading:20003451-Humans,
pubmed-meshheading:20003451-Immunoglobulin G,
pubmed-meshheading:20003451-Mice,
pubmed-meshheading:20003451-Mice, Inbred NOD,
pubmed-meshheading:20003451-Receptors, Tumor Necrosis Factor,
pubmed-meshheading:20003451-Recombinant Fusion Proteins,
pubmed-meshheading:20003451-Salivary Glands,
pubmed-meshheading:20003451-Sjogren's Syndrome
|
| pubmed:year |
2009
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| pubmed:articleTitle |
Local expression of tumor necrosis factor-receptor 1:immunoglobulin G can induce salivary gland dysfunction in a murine model of Sjögren's syndrome.
|
| pubmed:affiliation |
Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA. j.l.vosters@amc.uva.nl
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| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Intramural
|