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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2010-2-22
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pubmed:abstractText |
The treatment of brain tumors in childhood is frequently complicated by growth retardation with a high proportion of irradiation (Irr)-induced GH deficiency (GHD) resulting in reduced adult final height (AFH) even after GH therapy (GHT). In order to optimize future GHT protocols, more information on the factors influencing the growth response to GH in these children is needed. This retrospective study evaluated AFH and influencing auxological and treatment factors of a standardized daily biosynthetic GHT in childhood survivors of brain tumors with documented GHD after brain Irr.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1479-683X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
162
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
483-90
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pubmed:meshHeading |
pubmed-meshheading:19969557-Adolescent,
pubmed-meshheading:19969557-Adult,
pubmed-meshheading:19969557-Age Factors,
pubmed-meshheading:19969557-Belgium,
pubmed-meshheading:19969557-Body Height,
pubmed-meshheading:19969557-Brain Neoplasms,
pubmed-meshheading:19969557-Chi-Square Distribution,
pubmed-meshheading:19969557-Child,
pubmed-meshheading:19969557-Child, Preschool,
pubmed-meshheading:19969557-Databases, Factual,
pubmed-meshheading:19969557-Female,
pubmed-meshheading:19969557-Human Growth Hormone,
pubmed-meshheading:19969557-Humans,
pubmed-meshheading:19969557-Hypopituitarism,
pubmed-meshheading:19969557-Infant,
pubmed-meshheading:19969557-Male,
pubmed-meshheading:19969557-Patient Selection,
pubmed-meshheading:19969557-Pituitary Gland,
pubmed-meshheading:19969557-Radiotherapy,
pubmed-meshheading:19969557-Regression Analysis,
pubmed-meshheading:19969557-Retrospective Studies,
pubmed-meshheading:19969557-Sex Factors,
pubmed-meshheading:19969557-Statistics, Nonparametric,
pubmed-meshheading:19969557-Survivors
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pubmed:year |
2010
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pubmed:articleTitle |
Adult final height after GH therapy for irradiation-induced GH deficiency in childhood survivors of brain tumors: the Belgian experience.
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pubmed:affiliation |
Division of Pediatric Endocrinology, Department of Pediatrics, Catholic University of Louvain, Avenue G. Therasse, B-5530 Yvoir, Belgium. dominique.beckers@uclouvain.be
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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