Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2009-12-7
pubmed:abstractText
Combining of two measurement system of different scale in the mouse brain has been challenging issue due to the small size of the mouse brain. We present a novel approach to record brain activity and connectivity simultaneously by using intracranial electrode and flexible multichannel film electrode. 40 channel ultra-thin nanofabricated microelectrode covering the mouse skull was applied in this study. The null space in the microarray was cut off so that the secondary sensor or stimulator can approach to the brain. Hereby, we performed a simultaneous recording of local field potential and multichannel EEG recording in a freely moving mouse under pharmacologically driven absence seizure. A brain activity in the thalamus was depicted together with cortical EEG map. The connectivity levels between different cortical sites or between thalamus and cortical site were measured during seizure. The time lag map of cortical EEG with respect to the thalamus represents the propagation delay of the seizure.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1557-170X
pubmed:author
pubmed:issnType
Print
pubmed:volume
2009
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2934-6
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Simultaneous recording of brain activity and functional connectivity in the mouse brain.
pubmed:affiliation
Center for Neural Science, Korea Institute of Science and Technology, Seoul, Korea. sarangmina@kist.re.kr
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't