19958990

Source:http://linkedlifedata.com/resource/pubmed/id/19958990

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0017337, umls-concept:C0021212, umls-concept:C0023223, umls-concept:C0205419, umls-concept:C0220901, umls-concept:C0348013, umls-concept:C1511790
pubmed:issue	6
pubmed:dateCreated	2009-12-4
pubmed:abstractText	Wound healing in venous leg ulcer (VLU) is a multi-step process involving complex pathways. Scanty knowledge at molecular level hinders clinical assessment and treatment. Anomalous handling of local iron overload, as well as unbalancing in matrix metalloproteinases (MMPs) and transglutaminase, has a recognized role in VLU establishment. We selected a number of single nucleotide polymorphisms (SNPs) in candidate genes (HFE, FPN1, MMP12, and FXIII) involved in VLU to identify potentially prognostic markers by means of DNA-array technology.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8407742
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Cation Transport Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Factor XIII, http://linkedlifedata.com/resource/pubmed/chemical/HFE protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Histocompatibility Antigens Class I, http://linkedlifedata.com/resource/pubmed/chemical/MMP12 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 12, http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins, http://linkedlifedata.com/resource/pubmed/chemical/metal transporting protein 1
pubmed:status	MEDLINE
pubmed:month	Dec
pubmed:issn	1097-6809
pubmed:author	pubmed-author:CatozziLindaL, pubmed-author:GemmatiDonatoD, pubmed-author:GianesiniSergioS, pubmed-author:LDD, pubmed-author:ScapoliGian LGL, pubmed-author:TacconiGiovannaG, pubmed-author:ZamboniPaoloP
pubmed:issnType	Electronic
pubmed:volume	50
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1444-51
pubmed:meshHeading	pubmed-meshheading:19958990-Aged, pubmed-meshheading:19958990-Case-Control Studies, pubmed-meshheading:19958990-Cation Transport Proteins, pubmed-meshheading:19958990-Factor XIII, pubmed-meshheading:19958990-Female, pubmed-meshheading:19958990-Gene Expression Profiling, pubmed-meshheading:19958990-Genetic Predisposition to Disease, pubmed-meshheading:19958990-Histocompatibility Antigens Class I, pubmed-meshheading:19958990-Humans, pubmed-meshheading:19958990-Logistic Models, pubmed-meshheading:19958990-Male, pubmed-meshheading:19958990-Matrix Metalloproteinase 12, pubmed-meshheading:19958990-Membrane Proteins, pubmed-meshheading:19958990-Middle Aged, pubmed-meshheading:19958990-Odds Ratio, pubmed-meshheading:19958990-Oligonucleotide Array Sequence Analysis, pubmed-meshheading:19958990-Phenotype, pubmed-meshheading:19958990-Pilot Projects, pubmed-meshheading:19958990-Polymorphism, Single Nucleotide, pubmed-meshheading:19958990-Prognosis, pubmed-meshheading:19958990-Risk Assessment, pubmed-meshheading:19958990-Risk Factors, pubmed-meshheading:19958990-Severity of Illness Index, pubmed-meshheading:19958990-Varicose Ulcer, pubmed-meshheading:19958990-Wound Healing
pubmed:year	2009
pubmed:articleTitle	DNA-array of gene variants in venous leg ulcers: detection of prognostic indicators.
pubmed:affiliation	Haemostasis & Thrombosis Center, University of Ferrara, Ferrara, Italy. d.gemmati@unife.it
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't