rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
6
|
pubmed:dateCreated |
2009-12-4
|
pubmed:abstractText |
Heat shock protein 90 (HSP90) is a chaperone protein regulating several client proteins involved in thyroid cancer development. The purpose of this study was to mechanistically evaluate a novel, natural product drug with anticancer activity in thyroid cancer cell lines in vitro for future translational applications.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
1532-7361
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
146
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1196-207
|
pubmed:dateRevised |
2011-3-3
|
pubmed:meshHeading |
pubmed-meshheading:19958949-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:19958949-Apoptosis,
pubmed-meshheading:19958949-Cell Cycle,
pubmed-meshheading:19958949-Cell Line, Tumor,
pubmed-meshheading:19958949-Cell Proliferation,
pubmed-meshheading:19958949-Drug Screening Assays, Antitumor,
pubmed-meshheading:19958949-HSP90 Heat-Shock Proteins,
pubmed-meshheading:19958949-Humans,
pubmed-meshheading:19958949-Phytotherapy,
pubmed-meshheading:19958949-Plant Extracts,
pubmed-meshheading:19958949-Thyroid Neoplasms
|
pubmed:year |
2009
|
pubmed:articleTitle |
A novel HSP90 modulator with selective activity against thyroid cancers in vitro.
|
pubmed:affiliation |
Department of Surgery, University of Kansas Medical Center, Kansas City, KS 66160, USA.
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, N.I.H., Extramural
|