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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2009-12-4
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pubmed:abstractText |
Cyclophosphamide is a cornerstone in the treatment of many pediatric and adult malignancies, as well as in the treatment of refractory autoimmune conditions. Genetic factors are thought to play a role in the interindividual variation in both response and toxicities associated with cyclophosphamide-based therapies. This drug focus reviews the most compelling studies conducted on the pharmacogenetics of cyclophosphamide-based therapies. Broader pharmacogenomic studies are needed and may reveal additional factors important in susceptibility to toxicity and/or response to therapy.
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pubmed:grant |
http://linkedlifedata.com/resource/pubmed/grant/P50 CA125183-010004,
http://linkedlifedata.com/resource/pubmed/grant/P50 CA125183-020004,
http://linkedlifedata.com/resource/pubmed/grant/P50 CA125183-030004,
http://linkedlifedata.com/resource/pubmed/grant/P50 CA125183-040004,
http://linkedlifedata.com/resource/pubmed/grant/P50CA125183,
http://linkedlifedata.com/resource/pubmed/grant/R01 CA081485-05A1,
http://linkedlifedata.com/resource/pubmed/grant/R01 CA081485-06,
http://linkedlifedata.com/resource/pubmed/grant/R01 CA081485-07,
http://linkedlifedata.com/resource/pubmed/grant/R01 CA081485-08,
http://linkedlifedata.com/resource/pubmed/grant/R01 CA081485-09,
http://linkedlifedata.com/resource/pubmed/grant/R01 CA16783,
http://linkedlifedata.com/resource/pubmed/grant/R01 CA81485,
http://linkedlifedata.com/resource/pubmed/grant/U01 GM061393-060005,
http://linkedlifedata.com/resource/pubmed/grant/U01 GM061393-060010,
http://linkedlifedata.com/resource/pubmed/grant/U01 GM061393-070005,
http://linkedlifedata.com/resource/pubmed/grant/U01 GM061393-070010,
http://linkedlifedata.com/resource/pubmed/grant/U01 GM061393-080005,
http://linkedlifedata.com/resource/pubmed/grant/U01 GM061393-080010,
http://linkedlifedata.com/resource/pubmed/grant/U01 GM061393-090005,
http://linkedlifedata.com/resource/pubmed/grant/U01 GM061393-090010,
http://linkedlifedata.com/resource/pubmed/grant/U01 GM061393-100005,
http://linkedlifedata.com/resource/pubmed/grant/U01 GM061393-100010,
http://linkedlifedata.com/resource/pubmed/grant/U01 GM061393-10S10005,
http://linkedlifedata.com/resource/pubmed/grant/U01 GM061393-10S10010,
http://linkedlifedata.com/resource/pubmed/grant/U01GM61393
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1744-8042
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1897-903
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pubmed:dateRevised |
2011-9-26
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pubmed:meshHeading |
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pubmed:year |
2009
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pubmed:articleTitle |
Drug focus: Pharmacogenetic studies related to cyclophosphamide-based therapy.
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pubmed:affiliation |
University of Chicago, 900 East 57th Street, Room 7100, Chicago, IL 60637, USA.
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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