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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2009-12-16
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pubmed:abstractText |
Osteopontin (OPN) is expressed by fibroblast-like synoviocytes (FLS) in rheumatoid arthritis (RA), but its pathologic role is still obscure. The present study was undertaken to analyze the role of OPN in RA by focusing on its effects on cell-cell interactions between FLS and B lymphocytes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0004-3591
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
60
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3591-601
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pubmed:meshHeading |
pubmed-meshheading:19950274-Antibodies, Blocking,
pubmed-meshheading:19950274-Arthritis, Rheumatoid,
pubmed-meshheading:19950274-B-Lymphocytes,
pubmed-meshheading:19950274-Cell Adhesion,
pubmed-meshheading:19950274-Cell Line,
pubmed-meshheading:19950274-Coculture Techniques,
pubmed-meshheading:19950274-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:19950274-Fibroblasts,
pubmed-meshheading:19950274-Gene Silencing,
pubmed-meshheading:19950274-Humans,
pubmed-meshheading:19950274-Interleukin-6,
pubmed-meshheading:19950274-Osteoarthritis, Knee,
pubmed-meshheading:19950274-Osteopontin,
pubmed-meshheading:19950274-Peptides,
pubmed-meshheading:19950274-Protein Processing, Post-Translational,
pubmed-meshheading:19950274-RNA, Small Interfering,
pubmed-meshheading:19950274-Synovial Membrane,
pubmed-meshheading:19950274-Transfection
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pubmed:year |
2009
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pubmed:articleTitle |
Specifically modified osteopontin in rheumatoid arthritis fibroblast-like synoviocytes supports interaction with B cells and enhances production of interleukin-6.
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pubmed:affiliation |
Department of Orthopaedics, Osaka University Graduate School of Medicine, and Osaka Rosai Hospital, Osaka, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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