Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2009-11-30
pubmed:abstractText
We herein report a 3-year-old male demonstrating invasive cholangiocarcinoma (CC) associated with congenital biliary dilatation (CBD). A 3-year-old Japanese boy was admitted to our hospital with abdominal pain and vomiting. Computed tomography and magnetic resonance imaging demonstrated a dilated extrahepatic bile duct. A diagnosis of Todani's type 1a CBD was made. Intraoperative cholangiography demonstrated the presence of pancreaticobiliary maljunction but could not reveal any tumor lesion in the bile duct. The excision of extrahepatic bile duct and gallbladder and Roux-en-Y hepaticojejunostomy were performed. On gross inspection, we could not find any tumor lesion in the resected specimen. However, the postoperative histopathologic examinations confirmed the presence of well-differentiated tubular adenocarcinoma with lymphovascular invasion. Most of the carcinoma remained within the mucosal layer, and the carcinoma was identified at both the distal and proximal surgical margins of the bile duct. We scheduled additional surgery to eradicate the residual carcinoma, but informed consent for the extra surgery could not be obtained. A close follow-up with abdominal computed tomography has been going on without either additional surgery or adjuvant chemotherapy about for 1 year. The patient has so far been clinically doing well without any obvious symptoms of recurrent disease. To our knowledge, this report is the youngest case of CC associated with CBD.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1531-5037
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2202-5
pubmed:meshHeading
pubmed-meshheading:19944233-Age Factors, pubmed-meshheading:19944233-Anastomosis, Roux-en-Y, pubmed-meshheading:19944233-Bile Duct Neoplasms, pubmed-meshheading:19944233-Bile Ducts, Extrahepatic, pubmed-meshheading:19944233-Bile Ducts, Intrahepatic, pubmed-meshheading:19944233-Biliary Tract Surgical Procedures, pubmed-meshheading:19944233-Child, Preschool, pubmed-meshheading:19944233-Cholangiocarcinoma, pubmed-meshheading:19944233-Cholangiography, pubmed-meshheading:19944233-Common Bile Duct, pubmed-meshheading:19944233-Dilatation, Pathologic, pubmed-meshheading:19944233-Humans, pubmed-meshheading:19944233-Magnetic Resonance Imaging, pubmed-meshheading:19944233-Male, pubmed-meshheading:19944233-Neoplasm Invasiveness, pubmed-meshheading:19944233-Tomography, X-Ray Computed, pubmed-meshheading:19944233-Treatment Outcome
pubmed:year
2009
pubmed:articleTitle
Invasive cholangiocarcinoma identified in congenital biliary dilatation in a 3-year-old boy.
pubmed:affiliation
Department of Pediatric Surgery, Niigata City General Hospital, Niigata City, Niigata 950-1197, Japan. saikusa_nobuyuki@med.kurume-u.ac.jp
pubmed:publicationType
Journal Article, Case Reports