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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1991-3-15
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pubmed:abstractText |
The main aim of this study was to measure and explain geographic variations in the incidence of Legionnaires' disease in Scotland, particularly to help understand the source of non-outbreak infection. Between 1978 and 1986 the overall mean annual incidence rate was 7.9 per million (range 3.1-20.2), and for non-outbreak, non-travel cases it was 5.6. There were geographical variations by health board, by city and within cities, e.g. the mean annual incidence rate per million for non-travel, non-outbreak disease was 1.2 in Tayside Health Board, 3.7 in Lanarkshire, 5.6 in Lothian and 14.4 in Greater Glasgow. In Greater Glasgow Health Board non-travel cases lived in and around the city centre and in some postcode sectors there, the mean annual incidence rate exceeded 100. Travel-related cases lived in peripheral areas. These variations could not be explained by differences in access to and use of diagnostic services, surveillance, or host susceptibility (as reflected by socioeconomic status and frequency of other respiratory disease). The explanation probably lay in environmental factors, though differences in agent virulence were not excluded. The two main conclusions are, that non-outbreak cases were not truly sporadic, and that the space-time variations in incidence support the hypothesis that cooling towers were an important source of infection for non-travel, non-outbreak cases. If so such infection is potentially preventable.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/1993452-2915170,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1993452-3540109,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1993452-3543426,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1993452-3794366,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1993452-434635,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1993452-6124681,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1993452-6469623,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1993452-6747977,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1993452-7042762,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1993452-7153509,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1993452-7314031,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1993452-7469207
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0950-2688
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
106
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
45-61
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pubmed:dateRevised |
2010-9-7
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pubmed:meshHeading |
pubmed-meshheading:1993452-Adolescent,
pubmed-meshheading:1993452-Adult,
pubmed-meshheading:1993452-Aged,
pubmed-meshheading:1993452-Aged, 80 and over,
pubmed-meshheading:1993452-Disease Outbreaks,
pubmed-meshheading:1993452-Female,
pubmed-meshheading:1993452-Humans,
pubmed-meshheading:1993452-Incidence,
pubmed-meshheading:1993452-Legionnaires' Disease,
pubmed-meshheading:1993452-Male,
pubmed-meshheading:1993452-Middle Aged,
pubmed-meshheading:1993452-Scotland
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pubmed:year |
1991
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pubmed:articleTitle |
Variation in time and space of non-outbreak Legionnaires' disease in Scotland.
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pubmed:affiliation |
Division of Epidemiology and Public Health, School of Health Care Sciences, University of Newcastle upon Tyne.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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