Linked Life Data

19914548

Source:http://linkedlifedata.com/resource/pubmed/id/19914548

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2009-11-16
pubmed:abstractText
There is accumulating data on the clinical benefit of aromatase inhibitors in the adjuvant treatment of early-stage breast cancer in postmenopausal women. The Breast International Group (BIG) 1-98 study is a randomized, phase 3, double-blind trial comparing four adjuvant endocrine treatments of 5 years duration in postmenopausal women with hormone-receptor-positive breast cancer: letrozole or tamoxifen monotherapy, sequential treatment with tamoxifen followed by letrozole, or vice versa. This article summarizes data presented at the 2009 St. Gallen early breast cancer conference: an update on the monotherapy arms of the BIG 1-98 study, and results from the sequential treatment arms. Implications for daily practice from BIG 1-98 and from other adjuvant trials will be discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1532-3080
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
18 Suppl 3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S78-82
pubmed:meshHeading
pubmed-meshheading:19914548-Antineoplastic Agents, Hormonal, pubmed-meshheading:19914548-Aromatase Inhibitors, pubmed-meshheading:19914548-Breast Neoplasms, pubmed-meshheading:19914548-Chemotherapy, Adjuvant, pubmed-meshheading:19914548-Disease-Free Survival, pubmed-meshheading:19914548-Double-Blind Method, pubmed-meshheading:19914548-Drug Administration Schedule, pubmed-meshheading:19914548-Female, pubmed-meshheading:19914548-Follow-Up Studies, pubmed-meshheading:19914548-Humans, pubmed-meshheading:19914548-Nitriles, pubmed-meshheading:19914548-Postmenopause, pubmed-meshheading:19914548-Proportional Hazards Models, pubmed-meshheading:19914548-Receptors, Estrogen, pubmed-meshheading:19914548-Receptors, Progesterone, pubmed-meshheading:19914548-Tamoxifen, pubmed-meshheading:19914548-Triazoles
pubmed:year
2009
pubmed:articleTitle
Update of the BIG 1-98 Trial: where do we stand?
pubmed:affiliation
Breast Center, Cantonal Hospital, St. Gallen, Switzerland.
pubmed:publicationType
Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, Multicenter Study